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There are several types of research study designs, each with its inherent strengths and flaws. The study design used to answer a particular research question depends on the nature of the question and the availability of resources. In this article, which is the first part of a series on “study designs,” we provide an overview of research study designs and their classification. Sometimes randomisation isn’t practical or ethical, so researchers create partially-random or even non-random designs.
Frequently Asked Questions

An experimental research design helps researchers execute their research objectives with more clarity and transparency. The terms “prospective” versus “retrospective” studies can be confusing. To him/her, the process of enrolling cases and controls over a period of several months appears prospective. Or, at the very least, one must be clear that the terms relate to work flow for each individual study participant, and not to the study as a whole. There are some terms that are used frequently while classifying study designs which are described in the following sections.
Prospective versus retrospective study designs
Since school days’ students perform scientific experiments that provide results that define and prove the laws and theorems in science. These experiments are laid on a strong foundation of experimental research designs. Research study design is a framework, or the set of methods and procedures used to collect and analyze data on variables specified in a particular research problem.
Research Limitations
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In a within-subjects design, each participant experiences all conditions, and researchers test the same participants repeatedly for differences between conditions. In a between-subjects design, every participant experiences only one condition, and researchers assess group differences between participants in various conditions. A confounding variable is related to both the supposed cause and the supposed effect of the study.
A Quick Guide to Experimental Design 5 Steps & Examples
Observational studies are those where the researcher is documenting a naturally occurring relationship between the exposure and the outcome that he/she is studying. The researcher does not do any active intervention in any individual, and the exposure has already been decided naturally or by some other factor. For example, looking at the incidence of lung cancer in smokers versus nonsmokers, or comparing the antenatal dietary habits of mothers with normal and low-birth babies. In these studies, the investigator did not play any role in determining the smoking or dietary habit in individuals.
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Based on the direction of inquiry, study designs may be classified as forward-direction or backward-direction. In forward-direction studies, the researcher starts with determining the exposure to a risk factor and then assesses whether the outcome occurs at a future time point. For example, a researcher can follow a group of smokers and a group of nonsmokers to determine the incidence of lung cancer in each. For example, a researcher identifies a group of normal-weight babies and a group of low-birth weight babies and then asks the mothers about their dietary habits during the index pregnancy.
An experimental design where treatments aren’t randomly assigned is called a quasi-experimental design. These are pre-experimental research design, true experimental research design, and quasi experimental research design. Interventional studies are experiments where the researcher actively performs an intervention in some or all members of a group of participants. This intervention could take many forms – for example, administration of a drug or vaccine, performance of a diagnostic or therapeutic procedure, and introduction of an educational tool. For example, a study could randomly assign persons to receive aspirin or placebo for a specific duration and assess the effect on the risk of developing cerebrovascular events. The key difference between observational studies and experiments is that, done correctly, an observational study will never influence the responses or behaviours of participants.
Mistakes to Avoid While Designing Your Research
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Observational versus interventional (or experimental) studies
It can be difficult to separate the true effect of the independent variable from the effect of the confounding variable. Experimental designs are a set of procedures that you plan in order to examine the relationship between variables that interest you. How precisely you measure your dependent variable also affects the kinds of statistical analysis you can use on your data. How you manipulate the independent variable can affect the experiment’s external validity – that is, the extent to which the results can be generalised and applied to the broader world.
Experimental design means creating a set of procedures to systematically test a hypothesis. A good experimental design requires a strong understanding of the system you are studying. The ultimate goal of a research experiment is to gain valid and sustainable evidence. Therefore, incorrect statistical analysis could affect the quality of any quantitative research.
However, the difference between the two is the assignment of the control group. In this research design, an independent variable is manipulated, but the participants of a group are not randomly assigned. This type of research design is used in field settings where random assignment is either irrelevant or not required. Descriptive (or nonanalytical) studies, as the name suggests, merely try to describe the data on one or more characteristics of a group of individuals. These do not try to answer questions or establish relationships between variables. Examples of descriptive studies include a survey of dietary habits among pregnant women or a case series of patients with an unusual reaction to a drug.
Experimental research design is a framework of protocols and procedures created to conduct experimental research with a scientific approach using two sets of variables. Herein, the first set of variables acts as a constant, used to measure the differences of the second set. The best example of experimental research methods is quantitative research.
You could refer to the list as a checklist of what to avoid while designing your research. Here we predict that increasing temperature will increase soil respiration and decrease soil moisture, while decreasing soil moisture will lead to decreased soil respiration. This type of experimental research is commonly observed in the physical sciences. This website is using a security service to protect itself from online attacks.
How you apply your experimental treatments to your test subjects is crucial for obtaining valid and reliable results. To translate your research question into an experimental hypothesis, you need to define the main variables and make predictions about how they are related. By creating a research design, a researcher is also giving oneself time to organize the research, set up relevant boundaries for the study, and increase the reliability of the results. If any part of the research design is flawed, it will reflect on the quality of the results derived. Some variables, like temperature, can be objectively measured with scientific instruments.
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